Symptomatic relief of nausea & vomiting of functional, organic, infectious or dietary origin, induced by radio- or drug therapy & dopamine agonist used in Parkinson's disease.
Should be taken on an empty stomach: Take 15-30 min before meals.
Contraindications
Hypersensitivity. Prolactinoma. Patients w/ known existing prolongation of cardiac conduction intervals, significant electrolyte disturbances or underlying cardiac diseases eg, CHF; presence of GI haemorrhage, mechanical obstruction or perforation. Co-administration w/ QT-prolonging drugs, potent CYP3A4 inhibitors. Moderate or severe hepatic impairment.
Discontinue use if signs & symptoms of cardiac arrhythmia occurs. Increased risk of serious ventricular arrhythmias or sudden cardiac death; proarrhythmia. Not to be taken by patients w/ lactose/sorbitol intolerance, galactosemia or glucose/galactose malabsorption. Not to be taken simultaneously w/ antacids or antisecretory agents. Concomitant use w/ QT-prolonging drugs, potent CYP3A4 inhibitors, antacids or antisecretory agents. May affect ability to drive & use machines. Severe renal impairment. Pregnancy. Not recommended during lactation. Infant & childn <12 yr, <35 kg.
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